human bone marrow mesenchymal stem cells hbmscs (ATCC)
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Human Bone Marrow Mesenchymal Stem Cells Hbmscs, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 772 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/human bone marrow mesenchymal stem cells hbmscs/product/ATCC
Average 96 stars, based on 772 article reviews
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1) Product Images from "Serum DLX6-AS1 and miR-141-3p as early diagnostic biomarkers and regulators of delayed fracture healing (DFH)"
Article Title: Serum DLX6-AS1 and miR-141-3p as early diagnostic biomarkers and regulators of delayed fracture healing (DFH)
Journal: Journal of Orthopaedic Surgery and Research
doi: 10.1186/s13018-025-06478-5
Figure Legend Snippet: Interaction between DLX6-AS1 and miR-141-3p. A Predicted target sites. B Dual-luciferase reporter validation of the interaction. C Correlation analysis of serum DLX6-AS1 and miR-141-3p levels. D , E Expression of chondrogenic differentiation markers D , DLX6-AS1, and miR-141-3p E during hBMSCs chondrogenic differentiation. Data are presented as mean ± SD. Statistical analysis was performed using Student’s t-test or one-way ANOVA (n = 3). hBMSCs, Human bone marrow mesenchymal stem cells. * P < 0.05, ** P < 0.01, *** P < 0.001
Techniques Used: Luciferase, Biomarker Discovery, Expressing
Figure Legend Snippet: Effect of DLX6-AS1/miR-141-3p on hBMSCs functions. A qRT-PCR analysis of DLX6-AS1 and miR-141-3p after si-DLX6-AS1 treatment with or without miR-inhibition. B Proliferation level. C Apoptosis rate. D Expression of chondrogenic differentiation markers SOX9, COL2A1, and ACAN. Data are presented as mean ± SD. Statistical analysis was performed using Student’s t-test or one-way ANOVA (n = 3). hBMSCs, Human bone marrow mesenchymal stem cells. * P < 0.05, ** P < 0.01, *** P < 0.001
Techniques Used: Quantitative RT-PCR, Inhibition, Expressing
Figure Legend Snippet: VEGFA is a binding target of miR-141-3p. A Predicted binding sequence. B Dual-luciferase assay validation. C VEGFA expression levels in NFH (n = 96) vs DFH (n = 96) patients. D , E Correlation analyses between VEGFA and miR-141-3p or DLX6-AS1 (n = 96). Data are presented as mean ± SD. Statistical analysis was performed using Student’s t-test or one-way ANOVA. hBMSCs, Human bone marrow mesenchymal stem cells. NFH, normal fracture healing; DFH, delayed fracture healing. ** P < 0.01, *** P < 0.001
Techniques Used: Binding Assay, Sequencing, Luciferase, Biomarker Discovery, Expressing
Figure Legend Snippet: Functional role of the miR-141-3p/VEGFA axis in hBMSCs. A miR-141-3p and VEGFA abundance after transfection. B Proliferation assessed. C Apoptosis analysis. D Expression of chondrogenic differentiation markers after indicated treatments. Data are presented as mean ± SD. Statistical analysis was performed using Student’s t-test or one-way ANOVA (n = 3). hBMSCs, Human bone marrow mesenchymal stem cells. * P < 0.05, ** P < 0.01, *** P < 0.001
Techniques Used: Functional Assay, Transfection, Expressing